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Seaport Therapeutics Inc
101 Seaport Blvd., Floor 12
Phone: (302) 658-7581p:302 658-7581 BOSTON, MA  02110  United States Ticker: SPTXSPTX
Business Summary
Seaport Therapeutics, Inc. is a clinical-stage therapeutics company. The Company is focused on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. Its product candidate, GlyphAllo (SPT-300 or Glyph Allopregnanolone), is a novel, Glyphed oral prodrug of allopregnanolone, an endogenous molecule that has been clinically validated in third-party trials for the treatment of postpartum depression. GlyphAgo (SPT-320 or Glyph Agomelatine), is a novel, Glyphed oral prodrug of agomelatine, a clinically validated anxiolytic and antidepressant that is approved for the treatment of generalized anxiety disorder. It is also advancing Glyph2BLS (SPT-348 or Glyph 2-bromo-LSD), a novel, Glyphed oral prodrug of the non-hallucinogenic LSD analog 2-bromo-LSD, in preclinical studies for depressive disorders. GlyphAllo is designed to overcome the bioavailability limitations of allopregnanolone and be durable in MDD.
(Source: 6-K)

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202512/31/2025YesYes---

Industries
SIC Code Description
2834 Pharmaceutical preparations
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Director and Chairman of the Board Steven M.Paul 75 4/1/2024 4/1/2024
President, Chief Executive Officer, Director DaphneZohar 55 4/1/2024 4/1/2024
Chief Financial Officer Lauren A.White 47 11/1/2024 11/1/2024
8 additional Officers and Directors records available in full report.

Business Names
Business Name
Seaport Therapeutics Australia Pty Ltd
Seaport Therapeutics Securities Corporation
SPTX
SPTX, Inc.

General Information
Number of Employees: 58 (As of 4/1/2026)
Outstanding Shares: 53,027,817 (As of 12/31/2025)
Stock Exchange: NASD
Federal Tax Id: 992235719
Fax Number: (302) 655-5049


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Friday, May 29, 2026