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Tiziana Life Sciences Ltd - ADR
3Rd Floor, 11-12 St. James's Square
Phone: +44 2074952379p:+44 2074952379 LONDON, SW1Y 4LB  United Kingdom Ticker: TLSATLSA
Business Summary
Tiziana Life Sciences Ltd. is a United Kingdom-based clinical-stage biotechnology company. The Company develops transformative therapies for neurodegenerative and lung diseases. Its clinical pipeline includes drug assets for secondary progressive multiple sclerosis, Crohn's Disease and KRAS+ NSCLC. Its pipeline candidates include Foralumab (TZLS-401), Anti IL-6R mAb (TZLS-501) and Milciclib (TZLS-201). Foralumab (TZLS-401) is a fully human anti-CD3 monoclonal antibody (mAb) for the treatment of Crohn’s and neurodegenerative diseases. Its Anti IL-6R mAb (TZLS-501), a fully human mAb binds to both membrane-bound and soluble forms of IL-6R, an inflammatory cytokine driving chronic inflammation associated with autoimmune disease and cancer, reducing circulating levels of the IL-6 cytokine. Milciclib is a potent, small molecule inhibitor of multiple cyclin-dependent kinases (CDKs), tropomycinreceptor kinases and Src family kinases controlling cell growth and malignant progression of cancer.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-----

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202212/31/2022YesYes---

Industries
SIC Code Description
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Executive Chairman of the Board Gabriele M.Cerrone 50 4/24/2014 4/24/2014
Chief Executive Officer, Chief Scientific Officer, Executive Director KunwarShailubhai 65 6/12/2017 1/23/2015
Finance Director KeerenShah
5 additional Officers and Directors records available in full report.

General Information
Number of Employees: 9 (As of 12/31/2022)
Outstanding Shares: 102,272,614 (As of 12/31/2022)
Stock Exchange: NASD


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Wednesday, April 24, 2024