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Third Harmonic Bio Inc
1700 Montgomery Street, Suite 210
Phone: (209) 727-2457p:209 727-2457 SAN FRANCISCO, CA  94111  United States Ticker: THRDTHRD
Business Summary
Third Harmonic Bio, Inc. is a biopharmaceutical company. The Company is focused on advancing the next wave of medicine for inflammatory diseases through the development of novel, small-molecule inhibitors of KIT, a cell surface receptor that serves as the master regulator of mast cell function and survival. It is developing medicine for the treatment of inflammatory diseases, including dermal, respiratory, and gastrointestinal diseases. Its lead product candidate, THB335, is a titratable, oral, small molecule inhibitor. Dysfunctional mast cell activity has been implicated in the pathophysiology of a broad range of mast cell driven inflammatory disorders, including urticaria, asthma and gastrointestinal disorders, among others. THB335 maintains the nonclinical pharmacology and selectivity profile of THB001, with structural modifications that are designed to functionally block the site of reactive metabolite formation to mitigate hepatotoxicity risk.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
3/31/202512/31/2024YesYes---

Industries
SIC Code Description
2834 Pharmaceutical preparations
2836 Biological products, except diagnostic substances
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Independent Chairman of the Board MarkIwicki 58 5/1/2020 5/1/2020
Chief Executive Officer, Director Natalie C.Holles 52 8/9/2021 8/9/2021
Chief Financial and Business Officer and Principal financial officer Christopher M.Murphy 41 1/4/2024 1/4/2024
8 additional Officers and Directors records available in full report.

Business Names
Business Name
THB MS, Inc.
THRD

General Information
Number of Employees: 31 (As of 3/31/2025)
Outstanding Shares: 45,127,797 (As of 5/2/2025)
Shareholders: 6
Stock Exchange: NASD
Federal Tax Id: 834553503
Fax Number: (302) 655-5049


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Tuesday, May 13, 2025