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Oruka Therapeutics Inc
855 Oak Grove Ave., Suite 100
Phone: (650) 606-7910p:650 606-7910 MENLO PARK, CA  94025  United States Ticker: ORKAORKA
Business Summary
Oruka Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its lead program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, psoriatic arthritis (PsA), and other conditions. ORKA-001 is an extended half-life monoclonal antibody (mAb) designed to target IL-23p19. IL-23 is a pro-inflammatory cytokine that plays a critical role in the proliferation and development of T helper 17 (Th17) cells, which are the primary drivers of several autoimmune and inflammatory disorders, including PsO. IL-23 is composed of two subunits: a p40 subunit and a p19 subunit. ORKA-002 is an extended half-life mAb designed to target IL-17A and IL-17F (IL-17A/F).

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202412/31/2024YesYes---

Industries
SIC Code Description
2835 In vitro and in vivo diagnostic substances
8731 Commercial physical and biological research
2834 Pharmaceutical preparations

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Non-Executive Independent Chairman of the Board SamarthKulkarni 45 8/29/2024 8/29/2024
President, Chief Executive Officer, Director Lawrence O.Klein 42 8/29/2024 8/29/2024
Senior Vice President - Finance, Treasurer ArjunAgarwal 48 8/29/2024 8/29/2024
6 additional Officers and Directors records available in full report.

Business Names
Business Name
ABIO
ARCA biopharma, Inc.
ARCA biopharma, Inc.
5 additional Business Names available in full report.

General Information
Number of Employees: 28 (As of 12/31/2024)
Outstanding Shares: 37,440,510 (As of 2/28/2025)
Shareholders: 20
Stock Exchange: NASD
Federal Tax Id: 412193603
Fax Number: (302) 655-5049


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Friday, March 28, 2025