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Taysha Gene Therapies Inc
3000 Pegasus Park Drive, Suite 1430
Phone: (214) 612-0000p:214 612-0000 DALLAS, TX  75247  United States Ticker: TSHATSHA
Business Summary
Taysha Gene Therapies Inc is a clinical-stage biotechnology company, which is focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system. The Company’s lead clinical program, TSHA-102, is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder. The Company is evaluating TSHA-102 in the REVEALPhase I/II adolescent and adult clinical trial, which is a first-in-human, open-label, randomized, dose escalation and dose-expansion, multicenter study evaluating the safety and preliminary efficacy of TSHA-102 in female patients aged 12-years and older with Rett syndrome. It has acquired a worldwide right to a clinical-stage, intrathecally dosed AAV9 gene therapy program, TSHA-120, for the treatment of giant axonal neuropathy (GAN). It received orphan drug designation from the European Commission for TSHA-120 for the treatment of GAN.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202312/31/2023YesYes--Yes

Industries
SIC Code Description
8731 Commercial physical and biological research
2836 Biological products, except diagnostic substances

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Chairman of the Board, Chief Executive Officer Sean P.Nolan 55 12/16/2022 3/1/2020
President, Head of Research and Development, Director SukumarNagendran 57 12/16/2022 7/1/2020
Chief Financial Officer KamranAlam 45 8/1/2020 8/1/2020
4 additional Officers and Directors records available in full report.

General Information
Number of Employees: 52 (As of 12/31/2023)
Outstanding Shares: 187,018,275 (As of 3/19/2024)
Shareholders: 40
Stock Exchange: NASD
Federal Tax Id: 843199512


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Wednesday, April 24, 2024