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Prime Medicine Inc
60 First St.
Phone: (617) 465-0013p:617 465-0013 CAMBRIDGE, MA  02141  United States Ticker: PRMEPRME
Business Summary
Prime Medicine, Inc. is a biotechnology company engaged in creating and delivering gene editing therapies to patients. It deploys its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated one-time curative genetic therapies. It is advancing a set of high-value programs across its core areas of focus (hematology, immunology and oncology, liver, and lung). These include ex vivo hematopoietic stem cell (HSC) programs for the treatment of p47phox chronic granulomatous disease CGD and X-linked CGD; a lipid nanoparticle (LNP) Prime Editor for the treatment of Wilson’s Disease; a LNP or adeno-associated virus Prime Editors for the treatment of cystic fibrosis; and ex vivo T-cell therapies. PM359, its product candidate within its hematology, immunology and oncology area of focus, targets the p47phox variant of CGD. Its PM577 comprises a Prime Editor encapsulated as RNA cargo in a liver-targeted LNP.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202412/31/2024YesYes---

Industries
SIC Code Description
8731 Commercial physical and biological research
2836 Biological products, except diagnostic substances

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
President, Chief Executive Officer, Director Keith M.Gottesdiener 70 7/1/2020 7/1/2020
Co-Founder, Head of Prime Editing Platform AndrewAnzalone 37 1/1/2022 8/1/2020
Chief Financial Officer AllanReine 49 1/17/2024 1/17/2024
9 additional Officers and Directors records available in full report.

Business Names
Business Name
Prime Medicine Massachusetts Securities Corp.
Prime Medicine Securities Corp.
PRME

General Information
Number of Employees: 214 (As of 12/31/2024)
Outstanding Shares: 131,160,842 (As of 12/31/2024)
Shareholders: 77
Stock Exchange: NASD
Federal Tax Id: 843097762
Fax Number: (302) 655-5049


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Friday, April 18, 2025