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Xilio Therapeutics Inc
828 Winter Street, Suite 300
Phone: (302) 658-7581p:302 658-7581 WALTHAM, MA  02451  United States Ticker: XLOXLO
Business Summary
Xilio Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is engaged in discovering and developing masked immuno-oncology, or I-O, therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. Its pipeline products include Vilastobart, Efarindodekin alfa, XTX501, and masked T cell engagers. Vilastobart is an investigational masked, Fc-enhanced anti-CTLA-4 designed to block CTLA-4 and deplete regulatory T cells when activated (unmasked) in the tumor microenvironment (TME). XTX501 is a novel bispecific PD-1 / masked IL-2 designed to selectively stimulate PD-1 positive, antigen-experienced T cells and enhance their function. Its masked T cell engager programs consist of PSMA and STEAP1 with co-stimulation and CLDN18.2. The masked T cell engagers include molecules with one or more tumor-associated antigen (TAA) binding domains and a CD3 targeting domain.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202512/31/2025YesYes---

Industries
SIC Code Description
8731 Commercial physical and biological research
2836 Biological products, except diagnostic substances
2834 Pharmaceutical preparations

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Independent Chairman of the Board Sara M.Bonstein 45 1/6/2026 8/1/2021
President, Chief Executive Officer, Director ReneRusso 50 9/8/2023 1/1/2020
Chief Financial Officer and Operating Officer ChristopherFrankenfield 43 8/1/2024 3/29/2021
6 additional Officers and Directors records available in full report.

Business Names
Business Name
Akrevia Therapeutics
Xilio Development, Inc.
Xilio Securities Corporation
XILIO THERAPEUTICS INC
XLO

General Information
Number of Employees: 76 (As of 2/28/2026)
Outstanding Shares: 5,982,839 (As of 4/16/2026)
Shareholders: 23
Stock Exchange: NASD
Federal Tax Id: 851623397
Fax Number: (302) 655-5049


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Tuesday, May 12, 2026