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Applied Therapeutics Inc
545 5TH AVENUE, SUITE 1400
Phone: (212) 220-9226p:212 220-9226 NEW YORK, NY  10017  United States Ticker: APLTAPLT

Business Summary
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.

Scores and Ratings
FRISK®
Score
Z''
Score
PAYCE®
Score
DBT
Index
Moody's
Rating
Fitch
Rating
DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement
Last
Audit

News
SEC
Filings
Bankruptcy
Filings
Suit &
Judgment
Filings
Tax
Lien
Filings
12/31/202312/31/2023YesYes---

Officers and Directors

Title

Name

Age
Title
Date
Start
Date
Chairman of the Board, President, Chief Executive Officer, Founder ShoshanaShendelman 44 1/1/2016
Chief Financial Officer and Principal Financial Officer, Director Leslie D.Funtleyder 54 11/20/2023 6/1/2016
Chief Operating Officer and Chief Business Officer ConstantineChinoporos 57 12/28/2023 12/28/2023
7 additional Officers and Directors records available in full report.

General Information
Number of Employees: 25 (As of 12/31/2023)
Outstanding Shares: 105,886,831 (As of 3/5/2024)
Shareholders: 26
Stock Exchange: NASD
Fax Number: (302) 636-5454


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Thursday, March 28, 2024