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Prelude Therapeutics Inc
175 Innovation Boulevard
Phone: (302) 467-1280p:302 467-1280 WILMINGTON, DE  19805  United States Ticker: PRLDPRLD
Business Summary
Prelude Therapeutics Incorporated is a clinical-stage fully integrated oncology company built on a foundation of drug discovery to deliver novel precision cancer medicines to underserved patients. It has developed a diverse pipeline consisting of multiple distinct programs: kinases, targeted protein degraders, and precision antibody drug conjugates. Its product candidates include PRT3789, PRT2527 and PRT3645. PRT3789 is a highly selective degrader of SMARCA2 protein, which along with SMARCA4, controls gene regulation through chromatin remodeling. Its CDK9 program is an essential regulator of cancer-promoting transcriptional programs, including those driven by MCL1, MYC and MYB. PRT3645 is a brain and tissue penetrant molecule that potently targets CDK4/6 with a biased selectivity for CDK4. PRT2527 is designed to be a potent and selective CDK9 inhibitor. Its MCL1 candidate, PRT1419, is designed to be a potent and selective inhibitor of the anti-apoptotic protein, MCL1.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202312/31/2023YesYes--Yes

Industries
SIC Code Description
8731 Commercial physical and biological research
2834 Pharmaceutical preparations

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Independent Chairman of the Board Paul A.Friedman 80 7/1/2016 7/1/2016
President, Chief Medical Officer JaneHuang 50 4/4/2022 4/4/2022
Chief Executive Officer, Founder, Director KrishnaVaddi 57 1/1/2016 1/1/2016
7 additional Officers and Directors records available in full report.

General Information
Number of Employees: 128 (As of 12/31/2023)
Outstanding Shares: 109,834,848 (As of 2/9/2024)
Shareholders: 17
Stock Exchange: NASD
Federal Tax Id: 811384762
Fax Number: (302) 658-3989


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Thursday, April 18, 2024