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Syros Pharmaceuticals Inc
35 Cambridge Park Drive
Phone: (617) 744-1340p:617 744-1340 CAMBRIDGE, MA  02140  United States Ticker: SYRSSYRS
Business Summary
Syros Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on developing new standards of care for the frontline treatment of patients with hematologic malignancies. The Company is advancing Tamibarotene, a selective retinoic acid receptor alpha (RARa), agonist for which the Company is conducting SELECT-MDS-1, a Phase III clinical trial evaluating tamibarotene in combination with azacitidine in a genomically defined subset of patients with higher-risk myelodysplastic syndrome (HR-MDS), and for which it is conducting SELECT-AML-1, a randomized Phase II clinical trial evaluating tamibarotene in combination with venetoclax and azacitidine in a genomically defined subset of newly diagnosed patients with acute myeloid leukemia (AML). Its other assets include SY-2101 and SY-5609. The Company is seeking out-licensing opportunities for the further development of SY-5609, its highly selective and potent inhibitor of cyclin dependent kinase 7 (CDK7).

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202312/31/2023YesYes---

Industries
SIC Code Description
2834 Pharmaceutical preparations
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
President, Chief Executive Officer and Director NancySimonian
Independent Chairman of the Board Peter K.Wirth 72 1/27/2017 1/27/2017
Chief Operating Officer Kyle D.Kuvalanka
21 additional Officers and Directors records available in full report.

Subsidiaries
Business Name Address City State/Province Country
Tyme Technologies Inc 1 Pluckemin Way - Suite 103 BEDMINSTER NJ United States

Business Names
Business Name
Syros Pharmaceutials (Ireland) Limited
Syros Pharmaceuticals
Syros Securities Corporation
4 additional Business Names available in full report.

General Information
Number of Employees: 68 (As of 12/31/2023)
Outstanding Shares: 26,453,891 (As of 3/6/2024)
Shareholders: 73
Stock Exchange: NASD
Federal Tax Id: 453772460
Fax Number: (617) 744-1377


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Tuesday, April 23, 2024