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Stoke Therapeutics Inc
45 WIGGINS AVENUE
Phone: (781) 430-8200p:781 430-8200 BEDFORD, MA  01730  United States Ticker: STOKSTOK

Business Summary
Stoke Therapeutics, Inc. is a biotechnology company focused on addressing the underlying causes of severe genetic diseases by upregulating protein expression with ribonucleic acid-based medicines. Using its Targeted Augmentation of Nuclear Gene Output (TANGO) approach, the Company is developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its first compound, STK-001, is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. STK-001 is designed to upregulate NaV1.1 protein expression by leveraging the non-mutant (wild-type) copy of the SCN1A gene to restore physiological NaV1.1 levels, thereby reducing both the occurrence of seizures and non-seizure comorbidities. Its STK-002 is a ASO in preclinical development for the treatment of Autosomal Dominant Optic Atrophy (ADOA). STK-002 is designed to upregulate OPA1 protein expression by leveraging the non-mutant (wild-type) copy of the OPA1 gene.
(Source: 10-K)

Scores and Ratings
FRISK®
Score
Z''
Score
PAYCE®
Score
DBT
Index
Moody's
Rating
Fitch
Rating
DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement
Last
Audit

News
SEC
Filings
Bankruptcy
Filings
Suit &
Judgment
Filings
Tax
Lien
Filings
12/31/202312/31/2023YesYes---

Officers and Directors

Title

Name

Age
Title
Date
Start
Date
Independent Chairman of the Board Seth L.Harrison 62 7/1/2015 7/1/2015
Chief Executive Officer, Director Edward M.Kaye 74 10/1/2017 10/1/2017
Chief Financial Officer Stephen J.Tulipano 63 3/1/2019 3/1/2019
7 additional Officers and Directors records available in full report.

Business Names
Business Name
ASOTHERA PHARMACEUTICALS INC
STOK
Stoke Therapeutics MSC, Inc.

General Information
Number of Employees: 110 (As of 12/31/2023)
Outstanding Shares: 46,303,743 (As of 3/15/2024)
Shareholders: 6
Stock Exchange: NASD
Federal Tax Id: 471144582
Fax Number: (302) 531-3150
Email Address: info@stoketherapeutics.com


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Thursday, March 28, 2024