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Denali Therapeutics Inc
161 Oyster Point Blvd.
Phone: (650) 866-8547p:650 866-8547 SOUTH SAN FRANCISCO, CA  94080  United States Ticker: DNLIDNLI
Business Summary
Denali Therapeutics Inc. is a biopharmaceutical company. The Company is focused on developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for the treatment of neurodegenerative diseases and lysosomal storage diseases. It has developed a technology, called the TransportVehicle (TV), to address the BBB challenge. Its advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (MPS II or Hunter syndrome). Its TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for MPS IIIA (Sanfilippo syndrome) and DNL593 (PTV:PGRN) for frontotemporal dementia-granulin (FTD-GRN). Its small-molecule clinical development portfolio includes BIIB122/DNL151 (small molecule LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (small molecule eIF2B activator) for amyotrophic lateral sclerosis (ALS). It is also exploring programs in oncology, inflammation, and other diseases.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202412/31/2024YesYes--Yes

Industries
SIC Code Description
2836 Biological products, except diagnostic substances
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Independent Chairman of the Board Vicki L.Sato 75 8/1/2016 4/1/2015
President, Chief Executive Officer, Director Ryan J.Watts 48 1/1/2020 3/1/2015
Chief Financial Officer, Chief Operating Officer, Company Secretary Alexander O.Schuth 50 5/1/2022
5 additional Officers and Directors records available in full report.

Business Names
Business Name
Denali BBB Holding Limited
Denali Therapeutics CH GmbH
DNLI

General Information
Number of Employees: 422 (As of 12/31/2024)
Outstanding Shares: 145,215,391 (As of 2/21/2025)
Shareholders: 145
Stock Exchange: NASD
Federal Tax Id: 463872213
Fax Number: (302) 655-5049


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Friday, April 18, 2025