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TuHURA Biosciences Inc
10500 University Center Dr., Suite 110
Phone: (813) 875-6600p:813 875-6600 TAMPA, FL  33612  United States Ticker: HURAHURA
Business Summary
TuHURA Biosciences, Inc. is a Phase III registration-stage immuno-oncology company developing novel technologies to overcome resistance to cancer immunotherapy. Its lead innate immune agonist, IFx-2.0, is designed to overcome primary resistance to checkpoint inhibitors. It has initiated a single randomized placebo-controlled Phase III registration trial of IFx-2.0 administered as an adjunctive therapy to Keytruda (pembrolizumab) compared to Keytruda plus placebo in first-line treatment for advanced or metastatic Merkel Cell Carcinoma. It is leveraging its Delta Opioid Receptor technology to develop bi-specific antibody drug conjugates and antibody peptide conjugates targeting Myeloid Derived Suppressor Cells to inhibit their immune-suppressing effects on the tumor microenvironment to prevent T cell exhaustion and acquired resistance to checkpoint inhibitors and cellular therapies. It is also focused on the novel VISTA inhibiting mAb, known as TBS-2025.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
-Yes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
3/31/202512/31/2024YesYes---

Industries
SIC Code Description
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Independent Chairman of the Board James S.Manuso 76 10/18/2024 10/18/2024
Chief Executive Officer, Director JamesBianco 68 10/18/2024 10/18/2024
Chief Financial Officer DanDearborn 58 10/18/2024 10/18/2024
4 additional Officers and Directors records available in full report.

Subsidiaries
Business Name Address City State/Province Country
Yumanity Therapeutics, Inc. 790 Memorial Drive Cambridge MA United States
Adgero Biopharmaceuticals Holdings Inc 4365 US Highway 1 Ste 211 PRINCETON NJ United States
Kineta Inc 7683 Se 27Th Street, Suite 481 MERCER ISLAND WA United States
Kineta, Inc. 219 Terry Ave N Ste 300 Seattle WA United States

Business Names
Business Name
0959454 B.C. Ltd.
0959456 B.C. Ltd.
Adgero Biopharmaceuticals Holdings, Inc.
11 additional Business Names available in full report.

General Information
Number of Employees: 19 (As of 12/31/2024)
Outstanding Shares: 46,548,565 (As of 6/30/2025)
Shareholders: 606
Stock Exchange: NASD
Federal Tax Id: 990360497
Fax Number: (604) 202-1384


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Thursday, July 3, 2025